The effects of bilateral thoracic sympathectomy on cardiovascular system (an experimental study)
Turkiye Klinikleri Journal of Medical Sciences, cilt.29, sa.3, ss.632-636, 2009 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 29 Sayı: 3
- Basım Tarihi: 2009
- Dergi Adı: Turkiye Klinikleri Journal of Medical Sciences
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.632-636
- Anahtar Kelimeler: Sympathectomy, bradycardia, stellate ganglion
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Objective: Sympathectomy for palmar hyperhidrosis has been performed with long-term favorable results. The most common side effects of sympathectomy are compensatory sweating, gustatory sweating and cardiac changes including decreasing heart rate, systolic-diastolic and mean arterial pressure. The mechanism of bradycardia and other cardiac complications that develop after thoracic sympathectomy are still unclear. The aim of this study was to explain the effects of thoracic sympathectomy on cardiopulmonary functions and hemodynamics. Material and Methods: The rats (Ratus norvecus) were divided into two groups as the control group and the sympathectomy group. Prior to the operation, an indwelling arterial catheter was placed to monitor instant arterial blood pressure, heart rate, pulse oximeter and electrocardiogram (ECG). Bilateral thoracotomy was performed in both groups. Positive pressure ventilation was carried on via a nasal mask while the chest cavity was opened. Thoracic sympathectomy was performed only in the sympathectomy group. All rats were monitored and the results were recorded 60 minutes before and after the operation. Results: Heart rate and systolic blood pressure decreased significantly after T2 T3 ganglionectomy. A prolonged QT interval was also recorded (p< 0.05). The decrease in systolic and diastolic blood pressure was insignificant in group I (p> 0.05). SpO2 values were relatively decreased in all animals at the beginning of the operation (p< 0.05). No mortality was recorded. Conclusion: Surgeons should be aware of adverse effects such as bradycardia during thoracic sympathectomy. This study suggested that careful monitoring was required during thoracic sympathectomy and early postoperative period. Copyright © 2009 by Türkiye Klinikleri.