Hypoalbuminemia Leads to An Increased Risk of Mortality and Re-Operation within 3-Months in Patients 75< Years of Age after Surgery for Hip Fractures
Progress in Nutrition, cilt.23, sa.4, 2021 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 23 Sayı: 4
- Basım Tarihi: 2021
- Doi Numarası: 10.23751/pn.v23i4.12175
- Dergi Adı: Progress in Nutrition
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE
- Anahtar Kelimeler: hip fractures, hypoalbuminemia, frail elderly
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Background: The focus of this study is to ascertain a baseline nutritional level of adults 75 years old who are hospitalized for hip fracture surgery, and to assess the effects on the mortality rates and post-operative complications that require re-operation within 3 months of the initial surgery. Material and Methods: A total of 240 patients having surgery for fractured hips during 2017-2019 were identified. Patients’ characteristics, including pre-operative laboratory findings, complications and reoperation rates were assessed. Multivariate logistic regression analysis was used to establish the effect of hypoalbuminemia and total lymphocyte count on the rates of 3-month post-operative complications, re-operation and mortality. Results: Among patients studied, 153 had hypoalbuminemia (albumin levels <3.5 g/dL), and 87 showed normal albumin levels (albumin levels ≥3.5 g/dL). Patients in the hypoalbuminemia group were likely to be functionally dependent (p = 0.002) and had higher Charlson comorbidity scores (p = 0.006) than their counterparts. The American Society of Anesthesiologists score and albumin levels were significant predictors of re-operation (p = 0.013, p = 0.039). The increase in age by 1 year, albumin level <3.5 g/dL, and lymphocyte count <1500 cells/mm3 were associated with increased mortality rates (p = 0.012, p = 0.004, p = 0.002). Conclusion: Malnutrition is high in patients with hip fractures. In this study, hypoalbuminemia and lymphocyte count (<1500 cells/mm3) were directly associated with post-operative mortality rates and complications that required re-operation within 3 months of initial surgery.