Vogt-Kayanagi-Harada-Like Uveitis Induced by Dabrafenib/Trametinib Therapy for Cutaneous Malignant Melanoma
Ophthalmic Surgery Lasers and Imaging Retina, cilt.54, sa.8, ss.477-480, 2023 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 54 Sayı: 8
- Basım Tarihi: 2023
- Doi Numarası: 10.3928/23258160-20230524-01
- Dergi Adı: Ophthalmic Surgery Lasers and Imaging Retina
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, CINAHL, MEDLINE
- Sayfa Sayıları: ss.477-480
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
A 54-year-old woman with cutaneous malignant melanoma developed Vogt-Kayanagi-Harada (VKH)-like uveitis induced by dabrafenib/ trametinib therapy. Dabrafenib was discontinued but she continued to use trametinib due to the risk of disease progression. Intraocular inflammation resolved after cessation of dabrafenib and administration of topical and systemic corticosteroids. Our patient outlines the importance of recognizing VKH-like uveitis as a consequence of dabrafenib/ trametinib therapy in melanoma patients and highlights a question about the potential role of each drug in developing uveitis.