Effect of dexpanthenol on patient comfort in treatment of traumatic corneal abrasions Travmatik korneal abrazyon hastalarında dekspantenol kullanımının hasta konforuna olan etkisi

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Kilic D., Vural E., Albayrak G., Arslan M. E.

Pamukkale Medical Journal, cilt.14, sa.1, ss.43-48, 2021 (Scopus, TRDizin)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 14 Sayı: 1
  • Basım Tarihi: 2021
  • Doi Numarası: 10.31362/patd.730487
  • Dergi Adı: Pamukkale Medical Journal
  • Derginin Tarandığı İndeksler: Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.43-48
  • Anahtar Kelimeler: dexpanthenol, Traumatic corneal abrasion, visual analogue scale
  • Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
  • Sağlık Bilimleri Üniversitesi Adresli: Evet

Özet

Purpose: The aim in this study was to investigate if the use of dexpanthenol could play a role in the relief of pain in the treatment of corneal abrasions (CA). Materials and methods: Patients presenting to the ophthalmology department and had a diagnosis of CA were conducted in this retrospective, case-control study. A detailed ocular examination was done and pain severity was assessed using a visual analogue scale (VAS) score. In group 1, subjects were treated with only topical ofloxacin 0.3% while subjects in group 2 were treated with topical ofloxacin 0.3% and dexpanthenol. Foreign body sensation, photophobia, excessive lacrimation and VAS were documented on the first, third and seventh days of follow up examinations. Results: 70 patients were allocated into group 1 and 68 patients were allocated into group 2. There were significant differences in VAS scores between the groups on the first, third and seventh days of follow up (p=0.002, p<0.001 and p<0.001, respectively). VAS scores were lower in group-2. There were no statistically significant differences between two groups in terms of photophobia, foreign body sensation, excessive lacrimation (p>0.05). All patients were free of any complications. Conclusion: Although it was shown that adding topical dexpanthenol to the treatment regimen could permit faster pain relief in treating CAs, the prospective studies should be done.