Comparison of Optical Coherence Tomography Angiography Findings in Patients with Behçet’s Disease and Healthy Controls
Ocular Immunology and Inflammation, cilt.28, sa.5, ss.806-813, 2020 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 28 Sayı: 5
- Basım Tarihi: 2020
- Doi Numarası: 10.1080/09273948.2019.1635167
- Dergi Adı: Ocular Immunology and Inflammation
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CAB Abstracts, CINAHL, EMBASE, MEDLINE, Veterinary Science Database
- Sayfa Sayıları: ss.806-813
- Anahtar Kelimeler: Behcet's disease, foveal avascular zone, optical coherence tomography angiography, retinal microvasculature, vascular density
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Purpose: To investigate optical coherence tomography angiography (OCTA) findings in patients with Behçet’s disease (BD). Methods: Ninety-four eyes of 49 patients with BD and 53 eyes of 53 healthy subjects were included. Vascular density (VD), foveal avascular zone (FAZ) area, perifoveal capillary hypoperfusion, perifoveal capillary network disorganization, and FAZ irregularity were analyzed. Results: OCTA revealed retinal VD reduction and higher perifoveal capillary hypoperfusion, perifoveal capillary network disorganization and FAZ irregularity in ocular Behçet’s compared to nonocular Behçet’s (p =.000). However, compared to normal eyes, there was no difference between any OCTA measurements in nonocular BD patients. The mean area of FAZ was not different in any group (p =.266). In ocular Behçet, visual acuity was inversely correlated with FAZ area and FAZ irregularity. Conclusion: Retinal VD decreases and perifoveal microvascular network changes in ocular Behçet’s. FAZ irregularity may be a more valuable marker than FAZ area for indicating ocular involvement.