A facile and one-pot aqueous phase transfer of oleylamine capped Au NP with aminophenylboronic acid used as transfer and targeting ligand
Enzyme and Microbial Technology, cilt.148, 2021 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 148
- Basım Tarihi: 2021
- Doi Numarası: 10.1016/j.enzmictec.2021.109810
- Dergi Adı: Enzyme and Microbial Technology
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, Artic & Antarctic Regions, BIOSIS, Biotechnology Research Abstracts, CAB Abstracts, Chemical Abstracts Core, Chimica, Compendex, EMBASE, Environment Index, Food Science & Technology Abstracts, INSPEC, MEDLINE, Veterinary Science Database
- Anahtar Kelimeler: Nanoparticles, Functionalize, Phase transferring, Bacteria targeting, Catalytic activity
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Although various phase transfer techniques have been used to make hydrophobic nanoparticles (NPs) water-soluble. However, these techniques have been limited by inefficient surface modification strategy that often stable NPs in aqueous solutions. Herein, we report the use of 3-aminophenylboronic acid (3-APBA) as a hydrophilic ligand for phase transfer of oleylamine (OA) capped Au NPs (OA@Au NPs) from non-hydrolytic system into aqueous solutions. The 3-APBA capped Au NPs (3-APBA@Au NPs) was mainly characterized using different analytical techniques to substantiate the efficiency of the phase transfer procedure. In this simple procedure, 3-APBA molecule was simultaneously used as both phase transfer and targeting ligand for bacteria recognition in one step. In principle, while free electron pair of amin (:NH2) group of 3-APBAbind to surface of hydrophobic Au NPs for phase transfer, diol group can bind to glycan on the membrane of Staphylococcus aureus and Methicillin-resistant Staphylococcus aureus (MRSA) through proper cis-diol configuration. In addition, the resulting 3-APBA@Au NP can effectively catalyze the reduction of 4-nitrophenol (4-NP) to 4-aminophenol (4-AP) in the presence of sodium borohydride (NaBH4) in aqueous solution.