Detection of squamous cell carcinoma foci in a patient with dystrophic epidermolysis bullosa in18U Distrofik epidermolizis bülloza tanısı alan bir olguda skuamöz hücreli karsinom odağının 18 F-FDG PET/BT yöntemi ile saptanması
Molecular Imaging and Radionuclide Therapy, cilt.28, sa.2, ss.79-82, 2019 (Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 28 Sayı: 2
- Basım Tarihi: 2019
- Doi Numarası: 10.4274/mirt.galenos.2018.96658
- Dergi Adı: Molecular Imaging and Radionuclide Therapy
- Derginin Tarandığı İndeksler: Scopus, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.79-82
- Anahtar Kelimeler: F-18-FDG PET/CT, dystrophic epidermolysis bullosa, squamous cell carcinoma
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Dystrophic epidermolysis bullosa (DEB) is a rare, inherited skin fragility disorder characterized by blister formation in the sublamina densa. DEB is associated with aggressive squamous cell carcinoma (SCC) that has increased risk of metastases and poor prognosis. A 41-year-old woman with DEB underwent18F-fluoro-2-deoxy-glucose positron emission tomography/computed tomography (18F-FDG PET/BT). PET/CT showed increased 18 F-FDG uptakes in multifocal cutaneous lesions in both lower extremities. The patient was diagnosed with SCC via skin biopsy from the left lateral lower thigh. Ten months later, PET/CT showed increased FDG uptakes in the primary tumor area as well as the left inguinal and left supraclavicular lymph node regions.18F-FDG PET/CT seems to be useful for re-staging and planning appropriate therapeutic strategy in DEB-patients with SCC.