Evaluation of the quality of analgesia of intrapleural bupivacaine and bupivacaine + morphine administration TORAKOTOMI UYGULANAN OLGULARDA INTRAPLEVRAL BUPIVAKAIN ILE BUPIVAKAIN + MORFIN UYGULAMALARININ ANALJEZI KALITESININ DEGERLENDIRILMESI
Turk Anesteziyoloji ve Reanimasyon, cilt.23, sa.10, ss.491-496, 1995 (Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 23 Sayı: 10
- Basım Tarihi: 1995
- Dergi Adı: Turk Anesteziyoloji ve Reanimasyon
- Derginin Tarandığı İndeksler: Scopus
- Sayfa Sayıları: ss.491-496
- Anahtar Kelimeler: Bupivacaine, Intrapleural regional analgesia, Morphine
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
In our study, we aimed to compare the quality and the duration of analgesia of intrapleural bupivacaine and bupivacaine + morphine administration for relieving pain after thoracotomy. 30 cases of ASA I, were included in the study. Intrapleural catheter was placed properly before closing the thorax at the end of operation. Cases were randomly allocated in three groups. After the complete relief in the postoperative period 0.25 % bupivacaine of 2 mg/kg, 0.25 % bupivacaine of 2 mg/kg + 0.01 mg/kg morphine, and 20 mL 0.9 % NaCl solution as a placebo, were given to group I (n=10), group II (n=10), and group III (n=10) via intrapleural catheters, respectively. 10 mg/kg dipiron sodium were given to group III in every four hours. After the analgesic therapy all cases were monitored for systolic arterial pressure, diastolic arterial pressure, mean arterial pressure, heart rate, peripheral O2 saturation, vital capacity, forced expiratory volume in first second, arterial blood gases, Numeric Rating Scale and Prince Henry Pain Scoring values and these data were recorded. Following the intrapleural anaesthetic administration in the postoperative period, significant increases were determined in respiratory functions of group I and group II at the first and third hours (p<0.05) compared to the period before the administration of analgesic. But no significant changes in systolic, diastolic, mean arterial pressure, peripheral O2 saturation and arterial blood gases were determined (p>0.05). As a result, although in groups I and II adequate analgesia was obtained with single dose of bupivacaine only and with bupivacaine + morphine combination in early postoperative period after thoracotomy, there were no significant differences in the analgesia duration, thus we concluded that adding morphine to bupivacaine for intrapleural analgesia does not increase the quality and the duration of analgesia.