Retrospective Evaluation of Patients Diagnosed with Gestational Trophoblastic Disease in Our Clinic


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Turan K., Sargin B. A.

Van Medical Journal, cilt.32, sa.4, ss.227-232, 2025 (Scopus, TRDizin)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 32 Sayı: 4
  • Basım Tarihi: 2025
  • Doi Numarası: 10.5505/vmj.2025.41275
  • Dergi Adı: Van Medical Journal
  • Derginin Tarandığı İndeksler: Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.227-232
  • Anahtar Kelimeler: Gestational trophoblastic diseases, hydatiform mole, pregnancy, trophoblastic neoplasms
  • Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
  • Sağlık Bilimleri Üniversitesi Adresli: Evet

Özet

Inroduction: In this study, we were aimed to determine the clinical-pathological features by retrospectively evaluating the patients diagnosed with benign Gestational Trophoblastic Disease (GTD) in our clinic. Materials and Methods: This study retrospectively analyzed 11,319 pregnant patients who were admitted to our hospital between 2015 and 2019. 61 patients who were diagnosed with benign GTD, treated and followed up were included in the study. The patient’s a ges, hospital admission complaints, ultrasound findings, serum B-HCG values, blood groups, gravidity, parity, number of miscarriages, histological GTD type and treatments were analyzed. Results: In GTD cases, 11.5% were aged below 21 years, while 23% were above 35 years. 68.9% of the patients applied to our clinic with the complaint of vaginal bleeding, and 26% of the patient’s received diagnosis during follow-up visits. The blood group distribution of GTD patients did not significantly differ from that of the general population, indicating that blood group A may not be an in dependent risk factor. Conclusion: Although there are many studies in the literature on the etiology and incidence of GTD, differences are observed in the data obtained since most of the studies are clinic-based. There is a need to increase community-based studies on this issue. Upon initial admission, 78.7% of patients were clinically suspected of having GTD. Thanks to advances in diagnostic methods, earlier diagn osis of the disease has become possible, contributing to a reduction in complications arising from the disease. Raising public awareness about the importance of earlier medical consultations during pregnancy or in cases of pregnancy suspicion is crucial.