The Role of Cardiovascular Risk Factors and Risk Scoring Systems in Predicting Coronary Atherosclerosis
International Journal of Cardiovascular Sciences, cilt.34, sa.1, ss.32-38, 2021 (Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 34 Sayı: 1
- Basım Tarihi: 2021
- Doi Numarası: 10.36660/ijcs.20190134
- Dergi Adı: International Journal of Cardiovascular Sciences
- Derginin Tarandığı İndeksler: Scopus
- Sayfa Sayıları: ss.32-38
- Anahtar Kelimeler: Cardiovascular Diseases, Coronary Artery Diseases, Risk Factors, Atherosclerosis, Epidemiology, Coronary Angiography, Diabetes Mellitus, Hypertension, Renal Insufficiency, Heredity
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Background: Comparative data on the performance of cardiovascular risk scoring systems (CRSSs) in patients with severe coronary artery disease (CAD) are lacking. Objectives: To compare different CRSSs regarding their ability to discriminate patients with severe CAD. Method: A total of 414 patients (297 men; 61.3±12.3 years of age) undergoing coronary angiography were enrolled and evaluated for major risk factors. Cardiovascular risk and risk category were defined for each patient using the Framingham, Systemic Coronary Risk Evaluation (SCORE), and Pooled Cohort Risk Assessment Equation (PCRAE) tools. Severe CAD was defined as ≥ 50% stenosis in at least one major coronary artery and/or previous coronary stenting or coronary artery bypass grafting. A p< 0.05). However, when individual patients were classified as having low, intermediate, or high cardiovascular risk, the rate of patients in the high-risk group was significantly different between the PCRAE, Framingham, and SCORE tools (73.4%, 27.5%, and 37.9%, respectively; p <0.001). Discussion: PCRAE had higher positive and negative predictive values for detecting severe CAD in high-risk patients than the Framingham and SCORE tools. Conclusion: We can speculate that currently used CRSSs are not sufficient, and new scoring systems are needed. In addition, other risk factors, such as serum creatinine, should be considered in future CRSSs. (Int J Cardiovasc Sci. 2021; 34(1):32-38)