Duodenal ulcer healing with one week therapy Bir haftalik tedavi lie duodenal ulser iyilesmesi
Turkish Journal of Gastroenterology, cilt.9, sa.1, ss.46-49, 1998 (Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 9 Sayı: 1
- Basım Tarihi: 1998
- Dergi Adı: Turkish Journal of Gastroenterology
- Derginin Tarandığı İndeksler: Scopus, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.46-49
- Anahtar Kelimeler: Duodenal ulcer, Helicobacter pylori
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
The aim of this study was to investigate if acid-suppression therapy is needed after a Helicobacter pylori (H.pylori) eradication regimen. Fifty patients with H.pylori-positive-duodenal ulcer were included in this study. The patients were randomized into two groups of 25 patients. The same H.pylori eradication regimen (clarithromycin, amoxycillin and omeprazole) was given to both groups for one week. In addition, the patients in group II continued to take omeprazole for another 15 days. Antral and corporal biopsies were done on entry to the study and four weeks after treatment. Duodenal ulcer healed in all patients (100%) in both groups. H.pylori eradication was achieved in 19 (83.9%) cases in group I and 18 (78.2%) in group II. The difference between two groups was not significant. We conclude that one-week therapy is highly effective in duodenal ulcer healing.