Monocyte/HDL-cholesterol ratio predicts the definite stent thrombosis after primary percutaneous coronary intervention for ST-segment elevation myocardial infarction
Biomarkers in Medicine, cilt.9, sa.10, ss.967-977, 2015 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 9 Sayı: 10
- Basım Tarihi: 2015
- Doi Numarası: 10.2217/bmm.15.74
- Dergi Adı: Biomarkers in Medicine
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.967-977
- Anahtar Kelimeler: inflammation, monocyte to HDL ratio, PCI, ST elevation myocardial infarction, stent thrombosis
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Aim: We investigated the predictive value of monocyte count to HDL ratio (M/H ratio) for stent thrombosis (ST) in ST elevation myocardial infarction (STEMI). Patients & methods: 1170 STEMI patients treated with primary PCI were followed-up for a median of 37.2 months. Results: During follow-up, 112 patients were diagnosed as 'definite' ST. The rate of ST was significantly highest in the third M/H ratio tertile. In Cox regression analysis, adjusted for other factors, having an M/H ratio in third tertile had a 2.2-fold increased risk of ST. Kaplan-Meier analysis revealed the higher occurrence of ST in the third tertile compared with others (p <0.001). Conclusion: M/H ratio as a novel marker of inflammation seemed to be an independent predictor of ST in STEMI patients.