Are Neutrophil-to-Lymphocyte, Platelet-to-Lymphocyte, and Lymphocyte-to-Monocyte Ratios Predictive of Postoperative Complications and Mortality in Patients with Inflammatory Bowel Disease?

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Tuncer G. K., Tuncer K., Aydoğan S., KAMER K. E.

Turkish Journal of Colorectal Disease, cilt.33, sa.1, ss.13-17, 2023 (Scopus, TRDizin)

Özet

Aim: Although clinicians try to control inflammatory bowel diseases with medical treatment, surgical intervention may be required due to complications. Neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and lymphocyte-to-monocyte ratio (LMR) could be potential biomarkers of systemic inflammation in chronic diseases. This study aims to determine whether these ratios could be predictive of postoperative complications, mortality, and reoperation in patients operated on for inflammatory bowel disease complications. Method: Patients who were operated on for inflammatory bowel disease between 2010-2021 were analyzed retrospectively. The patients were divided into two groups: the Crohn's disease (CD) group and the ulcerative colitis (UC) group. Descriptive statistics were carried out between the two groups. Moreover, this study analyzed the effects of NLR, PLR, and LMR on short- and long-term postoperative complications, mortality, and reoperation. Results: A total of 42 patients were included in this study, 29 (69%) of them were men and 13 (31%) were women, and 24 (57%) of them were operated on for CD. NLR and PLR were significantly higher in patients with UC (p=0.031, p=0.009). However, none of these ratios were related to postoperative early and delayed complications, mortality, and reoperation in patients who were operated on for inflammatory bowel disease complications. Conclusion: NLR, PLR, and LMR cannot be used to predict postoperative complications, mortality, and reoperation in patients that were operated on for inflammatory bowel disease complications.