A practical and applicable desensitization scheme for ciprofloxacin with a glass of water
Allergologia et Immunopathologia, cilt.53, sa.5, ss.135-137, 2025 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 53 Sayı: 5
- Basım Tarihi: 2025
- Doi Numarası: 10.15586/aei.v53i5.1413
- Dergi Adı: Allergologia et Immunopathologia
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, DIALNET
- Sayfa Sayıları: ss.135-137
- Anahtar Kelimeler: quinolone, desensitization, ciprofloxacin
- Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Desensitization is an immunological process that creates temporary tolerance to a drug, which disappears once treatment is discontinued. Ciprofloxacin is a commonly used antibiotic, particularly for chronic lung diseases, yet there are very few desensitization protocols for it. Two ciprofloxacin desensitization schemes were developed a long time ago. However, these protocols are multistep, time-consuming processes, due to which a new protocol is required. We would like to present the practical oral desensitization protocol that we use. We included two patients with cystic fibrosis and bronchiectasis who required ciprofloxacin due to the presence of Pseudomonas aeruginosa in their sputum cultures. The desensitization process was successful and well-tolerated. This protocol is important because it addresses a significant gap in the literature.