The association between 25-hydroxyvitamin D levels and fetal malnutrition in term neonates


Eraslan D., SALİHOĞLU Ö., CAN E., Leijmann Ş. T., HATİPOĞLU S. S.

Medical Journal of Bakirkoy, cilt.14, sa.4, ss.339-346, 2018 (Scopus, TRDizin)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 14 Sayı: 4
  • Basım Tarihi: 2018
  • Doi Numarası: 10.4274/btdmjb.20170905075959
  • Dergi Adı: Medical Journal of Bakirkoy
  • Derginin Tarandığı İndeksler: Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.339-346
  • Anahtar Kelimeler: Nutrition assessment, cord blood, vitamin D Levels, fetal malnutrition
  • Sağlık Bilimleri Üniversitesi Adresli: Evet

Özet

Objective: The aim of this study is to determine the association between vitamin D deficiency in fetal malnutrition average for gestational age (AGA) neonates. Materials and Methods: The study was conducted on singleton term infants between March 1 and April 30, 2012. All of the neonates' cord-blood vitamin D levels were measured, and those identified as suffering from fetal malnutrition were placed into the study group, while the cord-blood vitamin D levels of well-nourished term newborns comprised the control group. Fetal malnutrition was detected using the Clinical Assessment of Nutritional Status Score (CANSCORE) method. Cord-blood vitamin D levels (ng/mL units) of newborns were measured and anthropometric results were recorded. Results: Total 110 term newborns were included in the study. Of these, 44 (40%) were part of the well-nourished nutrition group, with 66 (60%) in the malnutrition group. Birth weight, birth height, head circumference, weight gain during pregnancy, CANSCORE, and 25-hydroxyvitamin D [25(OH)Vit D] mean levels of the fetal malnourished group were found to be lower compared with the well-nourished group (p=0.0001). The maternal skin color and the maternal body mass index of the fetal malnourished group were found to differ significantly compared with the well-nourished group. Low cord-blood 25(OH)Vit D levels (p=0.002) and low head circumference (p=0.002) were found to be the factors that affect the presence of fetal malnutrition. Conclusion: 25(OH)Vit D levels are lower in with fetal malnourised AGA neonates compared with well-nourished term AGA neonates.