Isaacs' syndrome (Neuromyotonia) associated with peripheral neuropathy periferik nöropati ile isaacs sendromu (Nöromiyotoni) birlikteliǧi
Turkiye Fiziksel Tip ve Rehabilitasyon Dergisi, cilt.59, sa.4, ss.353-357, 2013 (SCI-Expanded, Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 59 Sayı: 4
- Basım Tarihi: 2013
- Doi Numarası: 10.4274/tftr.83435
- Dergi Adı: Turkiye Fiziksel Tip ve Rehabilitasyon Dergisi
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.353-357
- Anahtar Kelimeler: Isaacs' syndrome, neuromyotonia, peripheral neuropathy
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Isaacs's syndrome (neuromyotonia), which is characterized by peripheral nerve hyperexcitability, is a rare condition of spontaneous and continuous muscle fibre activity. This syndrome is associated with myokymia, muscle cramps and stiffness, delayed muscle relaxation after contraction, muscle weakness, and hyperhydrosis. We report two siblings with Isaacs' syndrome associated with peripheral neuropathy gait disturbance, distal muscle weakness, neuromyotonia, muscle spasms, myokymia and hyperhydrosis. In both patients, neuromyotonic discharges were recorded by needle electromyography and axonal sensorimotor peripheral neuropathy was diagnosed electrophysiologically. In this study, a rare case of Isaacs'syndrome (neuromyotonia) associated with peripheral neuropathy is emphasized. © Turkish Journal of Physical Medicine and Rehabilitation, Published by Galenos Publishing.