Levels of circulating intercellular adhesion molecule-1 in patients with Behçet's disease


SAĞLAM K., Yilmaz I. M., Saglam A., Ulgey M., Bulucu F., Baykal Y.

Rheumatology International, cilt.21, sa.4, ss.146-148, 2002 (SCI-Expanded, Scopus)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 21 Sayı: 4
  • Basım Tarihi: 2002
  • Doi Numarası: 10.1007/s00296-001-0148-9
  • Dergi Adı: Rheumatology International
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.146-148
  • Anahtar Kelimeler: circulating intercellular adhesion molecule-1 Behcet's disease
  • Sağlık Bilimleri Üniversitesi Adresli: Hayır

Özet

The purpose of this study was to investigate the possible relationship between circulating intercellular adhesion molecule-1 (cICAM-1) plasma levels and Behget's disease. Plasma levels of cICAM-1 were measured in 44 patients with Behçet's disease and in 30 healthy controls, cICAM-1 levels were higher in patients with Behçet's disease than in the controls (P = 0.001). The difference was more marked between patients with active Behçet's disease and controls (P < 0.001). cICAM-1 levels were also higher in patients with active Behçet's disease than in those with inactive disease (P < 0.001). cICAM-1 seems to be related to disease activity in Behçet's disease. It may be useful in assessing disease activity in Behçet's disease, as well as in monitoring response to treatment.