Polymerase chain reaction based diagnosis of primary gastric tuberculosis in an 80-year-old woman: A case report and review of the literature


BAYLAN O., Kilciler G., ALBAY A., Tuzun A., Kisa O., Dagalp K.

New Microbiologica, cilt.32, sa.2, ss.217-221, 2009 (SCI-Expanded, Scopus)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 32 Sayı: 2
  • Basım Tarihi: 2009
  • Dergi Adı: New Microbiologica
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.217-221
  • Anahtar Kelimeler: Primary gastric tuberculosis, Mycobacterium tuberculosis complex, Polymerase chain reaction
  • Sağlık Bilimleri Üniversitesi Adresli: Hayır

Özet

The patient had a two month history of gastrointestinal symptoms. Upper gastrointestinal endoscopy disclosed 5 mm nodular lesions were seen in the prepyloric area. On pathological examination, two granulomatous lesions were detected in biopsy specimen. Ehrlich Ziehl-Neelsen staining and cultures of the biopsy material were negative, but polymerase chain reaction (PCR) for Mycobacterium tuberculosis complex DNA was positive. Clinical diagnosis of primary gastric tuberculosis (PGTb) was supported by positive PCR assay and histopathological findings. After antituberculosis treatment, nodular lesions were not detected. The diagnosis of PGTb was confirmed definitively by the success of treatment and repeated endoscopic examination.