Depressive symptoms in first episode schizophrenia: A six-month follow-up study İlk atak şizofrenide depresif belirtiler: Alti aylik i̇zleme çalişmasi


UZUN Ö., Zincir N., Cansever A., Özflahin A.

Klinik Psikofarmakoloji Bulteni, cilt.12, sa.2, ss.64-68, 2002 (Scopus, TRDizin)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 12 Sayı: 2
  • Basım Tarihi: 2002
  • Dergi Adı: Klinik Psikofarmakoloji Bulteni
  • Derginin Tarandığı İndeksler: Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.64-68
  • Anahtar Kelimeler: Depressive symptoms, First-episode schizophrenia, Negative symptoms, Positive symptoms
  • Sağlık Bilimleri Üniversitesi Adresli: Hayır

Özet

Objective: In this study we aimed to find the prevalence of depressive symptoms in first-episode schizophrenia, and to determine the relationship between depressive symptoms and positive/negative symptoms of schizophrenia. Method: Twenty-six patients receiving neuroleptic medication were followed-up throughout six months. Schizophrenia was diagnosed by using the Structured Clinical Interview for DSM-IV (SCID-I). Severity of psychosis, positive symptoms, and negative symptoms were measured using of the Brief Psychiatric Rating Scale, the Scale for the Assessment of Positive Symptoms, and the Scale for the Assessment of Negative Symptoms, respectively. Depressive symptoms were assessed by using the Hamilton Rating Scale for Depression and Calgary Depression Scale. Results: At pretreatment, the frequency of depressive symptoms was 69.2%. The results indicated that depressive symptoms were correlated with severity of schizophrenia and with positive symptoms at beginning and at the end of the study. With neuroleptic treatment, depressive and psychotic symptoms decreased significantly during follow-up. Conclusion: The frequency of depressive symptoms in first-episode schizophrenia was high. Moreover, a positive correlation was found between depressive symptoms and severity of schizophrenia. Thus, we concluded that depressive symptoms might be core symptom of schizophrenia.