Evaluation of the Characteristics of Citrobacter spp. Bloodstream Infections in Pediatric Patients Çocuk Hastalarda Citrobacter spp. Kan Dolaşım Yolu Enfeksiyonlarının Özelliklerinin Değerlendirilmesi


Özer A., Özenen G. G., AĞIN H., Kara A. A., Şahinkaya Ş., Cem E., ...Daha Fazla

Cocuk Enfeksiyon Dergisi, cilt.18, sa.4, 2024 (ESCI, Scopus, TRDizin)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 18 Sayı: 4
  • Basım Tarihi: 2024
  • Doi Numarası: 10.5578/ced.20240404
  • Dergi Adı: Cocuk Enfeksiyon Dergisi
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
  • Sağlık Bilimleri Üniversitesi Adresli: Evet

Özet

Objective: Citrobacter spp. is a gram-negative bacterium from the Enterobacteriaceae family that is an opportunistic pathogen causing infections such as urinary tract, respiratory tract, surgical wounds and bacteremia. Although Citrobacter strains colonizing the human gastrointestinal tract are traditionally thought to have low virulence, they can cause serious clinical pictures, especially in immunocompromised, neonatal and elderly groups. In recent years, it has been shown that the association with mortality is higher with the spread of multidrug resistant strains. In Türkiye, studies evaluating the characteristics of bloodstream infections caused by Citrobacter spp. in pediatric patients are rare. The aim of our study was to determine the clinical and laboratory findings, antibiotic resistance, mortality rate and prognosis of hospitalized patients with Citrobacter spp. in blood culture samples. Material and Methods: Patients hospitalized in a tertiary care hospital between December 2013 and April 2021 with Citrobacter spp. growth in blood cultures were included in this study. Age, sex, comorbidities, presence of central venous catheter, use of mechanical ventilation, total parenteral nutrition, laboratory findings, duration of hospitalization, other sterile field culture samples, culture antibiograms, and antimicrobial treatments were determined as variables and recorded on pre-prepared forms.