Clarithromycine-induced ventricular tachycardia in a geriatric patient using multiple drugs Çoklu ilaç kullanımı olan geriatrik hastada klaritromisin’e bağlı ventriküler taşikardi
Journal of Clinical and Analytical Medicine, cilt.7, sa.4, ss.560-562, 2016 (Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 7 Sayı: 4
- Basım Tarihi: 2016
- Doi Numarası: 10.4328/jcam.4400
- Dergi Adı: Journal of Clinical and Analytical Medicine
- Derginin Tarandığı İndeksler: Scopus, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.560-562
- Anahtar Kelimeler: Clarithromycine, Long QT Syndrome, Adverse Drug Interaction
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Long QT syndrome is a cardiac repolarization disorder, which can be either id-iopathic or congenital, and cause sudden cardiac death. The iatrogenic form is generally associated with drugs or electrolyte imbalance. Although prolonged QT interval is frequently seen due to antiarrhythmic agents, it can also be seen with antibiotics or anti-epileptics. Adverse drug interaction can manifest in several clinicopathological forms in elder individuals. In such cases, potential adverse effects of drugs used should be taken into consideration before prescribing additional drugs. Here, we present a case of clarithromycine-induced ventricular arrhythmia accompanied by QT prolongation on the third day of therapy, and the subsequent therapeutic approach, in a 91-year-old man. The patient was taking multiple drugs due to comorbid conditions and was prescribed clarithromycine therapy in the intensive care unit.