Can inflammatory indexes predict the spontaneous passage of common bile duct stones?
Scottish Medical Journal, cilt.68, sa.4, ss.159-165, 2023 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 68 Sayı: 4
- Basım Tarihi: 2023
- Doi Numarası: 10.1177/00369330231186434
- Dergi Adı: Scottish Medical Journal
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, CAB Abstracts, Food Science & Technology Abstracts
- Sayfa Sayıları: ss.159-165
- Anahtar Kelimeler: ERCP, common bile duct stone, spontaneous passage
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Objectives: We aimed to determine whether inflammatory indexes (II), including the neutrophil–lymphocyte ratio (NLR), the C-reactive protein (CRP) to albumin ratio (CAR), the CRP–lymphocyte ratio (CLR), and the systemic immune-inflammation index (SIII) can be diagnostic for common bile duct stones (CBDSs) excretion before endoscopic retrograde cholangiopancreatography (ERCP). Backgrounds: Because of the spontaneous clearance, it is mandatory to ascertain the presence of CBDSs before ERCP. Methods: Retrospectively, we evaluated two groups. Group A included 96 records in which CBDSs existed in magnetic resonance cholangiopancreatography (MRCP) and ERCP. Group B included 36 records in which CBDSs existed in MRCP but not ERCP. IIs were calculated on presentation and before ERCP. Results: Stone detection in ERCP had a 3.992-fold (95% 1.769–9.007) higher probability with a stone larger than 3.25 mm in MRCP. Before ERCP, CAR, and CLR values were higher in group A than in group B (3.88 [1.25–14.14] and 1.24 [0.50–9.66], p = 0.027 versus 8.79 [2.19–35] and 2.67 [1.02–20.05], p = 0.029, respectively). Higher CRP, CAR, and CLR values were considered significant for detecting a stone in ERCP (AUC: 0.627 [0.519–0.739], 0.625 [0.513–0.737], and 0.624 [0.514–0.734], respectively). Conclusion: Low CRP, CAR, and CLR values might associate with the spontaneous migration of CBDS.