The association between monocyte HDL ratio and albuminuria in diabetic nephropathy
Pakistan Journal of Medical Sciences, cilt.37, sa.4, ss.1128-1132, 2021 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 37 Sayı: 4
- Basım Tarihi: 2021
- Doi Numarası: 10.12669/pjms.37.4.3882
- Dergi Adı: Pakistan Journal of Medical Sciences
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CAB Abstracts, EMBASE, Veterinary Science Database, Directory of Open Access Journals
- Sayfa Sayıları: ss.1128-1132
- Anahtar Kelimeler: Albuminuria, Diabetic nephropathy, Monocyte-to-HDL ratio
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Objectives: We aimed to investigate whether Monocyte-to-HDL ratio (MHR) had an association with albuminuria in patients with diabetic nephropathy (DN). Methods: Diabetic patients, who had admitted to the outpatient clinic of general internal disease department between September 2017-February 2018 and had their spot urinary albumin/creatinine ratio measured, were examined retrospectively. Patients were separated based on the presence of DN. Patients with DN were grouped as Stage-I, Stage-II and Stage-III chronic kidney disease (CKD). Groups were compared in terms of MHR. The presence of a correlation between MHR and albuminuria was investigated. Results: MHR was found to be higher in the DN (n=85) group compared to Non-DN group. (16.2±5.5 vs. 14.3±4, p=0.037) And there was no significant difference in Stage-I, Stage-II and Stage-III CKD groups in terms of MHR. (15.2± 3.4, 16.1±6.0, 17.1±6.0, p=0.485). No significant correlation was found between MHR and albuminuria in DN and non-DN groups (p=0.634, r=0.052; p=0.553, r=-0.059). Conclusions: DN group had higher MHR than non-nephropathy group, whereas, there was no correlation between albuminuria and MHR.