Uncommon coexistence causing a challenge in the diagnosis of acromegaly
Acta Medica Mediterranea, cilt.31, sa.2, ss.409-411, 2015 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 31 Sayı: 2
- Basım Tarihi: 2015
- Dergi Adı: Acta Medica Mediterranea
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.409-411
- Anahtar Kelimeler: Ankylosing, spondylitis, acromegaly, arthralgia, sacroiliitis
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Introduction: Acromegaly is a rare chronic disease caused by hypersecretion of growth hormone and insulin like growth factor 1. Patients with acromegaly generally exhibit acral enlargement, increased skin thickness, and facial bony deformities, including prognathism. Other features include cardiovascular disease, hypogonadism, carpal tunnel syndrome, diabetes mellitus and arthropathy. The clinical diagnosis is often delayed because of the slow progression of the signs of acromegaly. Joint symptoms are amongst the most frequent clinical manifestations. Acromegalic arthropathy ranges from osteoarthritis to arthralgia to fractures. Case presentation: In this report we aimed to present a 28 year old man with acromegaly and ankylosing spondylitis in whom acromegalic arthropathy was masked because of the very rare coexistence of ankylosing spondylitis and acromegaly. Conclusion: Acromegalic arthropathy is one of the most frequent and severe cause of morbidity and disability in patients with acromegaly. This rare chronic endocrinopathy should be kept in mind in patients with spondyloarthritis especially with resistant peripheral arhritis. Early diagnosis and effective treatment of acromegaly is very important to assure a favorable outcome and to prevent long term complications.