Effects of CyberKnife therapy for vestibular schwannoma on hearing: A retrospective study
Journal of Laryngology and Otology, cilt.132, sa.9, ss.796-801, 2018 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 132 Sayı: 9
- Basım Tarihi: 2018
- Doi Numarası: 10.1017/s0022215118001500
- Dergi Adı: Journal of Laryngology and Otology
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.796-801
- Anahtar Kelimeler: Vestibular Schwannoma, CyberKnife Radiosurgery, Hearing Loss, Stereotactic Radiosurgery
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Objectives To evaluate the effects of CyberKnife stereotactic radiotherapy for the treatment of vestibular schwannoma on hearing, as evaluated by audiological tests.Methods Patients with vestibular schwannoma were evaluated before and after CyberKnife radiosurgery. Evaluation included pure tone thresholds, speech discrimination scores, auditory brainstem responses and radiological signs.Results The study comprised 26 patients diagnosed with vestibular schwannoma and subsequently treated with CyberKnife radiosurgery. The mean follow-up time was 16.4 months. The mean post-treatment hearing preservation rate was 69.23 per cent. There was no significant relationship between hearing loss after treatment and patient age, radiation dosage during treatment, or size of tumour. With regard to auditory brainstem responses, patients with hearing loss following treatment had a significantly higher inter-peak latency between waves I-III than patients with preserved hearing.Conclusion Stereotactic CyberKnife radiosurgery is an excellent alternative treatment modality for patients with vestibular schwannoma, and results in acceptable preservation of hearing. Residual hearing following CyberKnife therapy is not significantly affected by factors such as age, size of tumour or dosage of treatment.