Long-term results of endoscopic resection for type i gastric neuroendocrine tumors
Journal of Surgical Oncology, cilt.109, sa.2, ss.71-74, 2014 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 109 Sayı: 2
- Basım Tarihi: 2014
- Doi Numarası: 10.1002/jso.23477
- Dergi Adı: Journal of Surgical Oncology
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.71-74
- Anahtar Kelimeler: endoscopic mucosectomy, neuroendocrine tumors, gastric carcinoid
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Background A number of different therapies, including endoscopic resection, have been suggested for the treatment of Type 1 gastric neuroendocrine tumors (NETs). The current study aimed to determine the long-term efficacy of endoscopic resection for Type 1 gastric NETs. Methods Twenty-two patients (from 1999 to 2012) with Type 1 gastric NETs were included in the study. All patients were treated with endoscopic resection and received regular followed-up appointments at a tertiary referral center. Results All patients were initially diagnosed with hypergastrinemia, atrophic gastritis and intestinal metaplasia. Polyps' diameters were >1 cm in 4 patients, and between 0.5 and 1 cm in 18 patients. All detectable lesions were successfully resected. One patient required surgery due to gastric perforation during endoscopic mucosal resection. Recurrence was detected in four patients (18%) and endoscopic resection was performed again. Local or distant metastasis was not observed in any patient during follow-up. Median follow-up time was 7 years, with a maximum of 14 years. Seventeen patients (78%) completed a 5-year follow-up period, and overall disease-free survival rate was 100%. Conclusions Long-term follow-ups with 22 patients suggest that endoscopic resection of Type 1 gastric NETs is a safe and effective treatment option with a relatively low recurrence rate. J. Surg. Oncol. 2014 109:71-74. © 2013 Wiley Periodicals, Inc. © 2013 Wiley Periodicals, Inc.