An Additional LDL-Lowering Effect of Amlodipine; Not only an Antihypertensive?
Clinical and Experimental Hypertension, cilt.35, sa.6, ss.449-453, 2013 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 35 Sayı: 6
- Basım Tarihi: 2013
- Doi Numarası: 10.3109/10641963.2012.746355
- Dergi Adı: Clinical and Experimental Hypertension
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.449-453
- Anahtar Kelimeler: amlodipine, valsartan, hypertension, hyperlipidemia, LDL
- Sağlık Bilimleri Üniversitesi Adresli: Hayır
Özet
Hypertension is a modifiable risk factor for cardiovascular diseases and is associated with several metabolic disorders like dyslipidemia. Higher levels of triglyceride and low-density lipoprotein (LDL) are quite strong factors for the development of cardiovascular diseases. In this study, we investigated the effects of valsartan and amlodipine on the lipid profile in patients with newly diagnosed essential hypertension. We observed a beneficial effect of amlodipine on the lipid profile with a significant reduction of LDL compared to valsartan. In the treatment of hypertension, prior knowledge of the plasma cholesterol levels can be important in antihypertensive drug choice. © 2013 Informa Healthcare USA, Inc.