P wave duration and dispersion in multiple sclerosis
Clinical Autonomic Research, cilt.15, sa.6, ss.382-386, 2005 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 15 Sayı: 6
- Basım Tarihi: 2005
- Doi Numarası: 10.1007/s10286-005-0283-6
- Dergi Adı: Clinical Autonomic Research
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.382-386
- Anahtar Kelimeler: multiple sclerosis, autonomic dysfunction, P wave dispersion
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Background: Multiple sclerosis (MS) has been reported to be associated with extensive autonomic dysfunction as well as to involve the cardiovascular system. In this study we compared P wave duration and dispersion (PWD) of MS patients to healthy control subjects. Method: Thirty-one MS patients (mean age 35 ± 9 years) and 33 healthy control subjects (mean age 34 ± 7 years) were included in the study. Twelve-lead surface ECG recording (paper speed of 50 mm/s) was obtained from all participants. The change in maximum and minimum P wave duration was measured manually and the difference between the two values was defined as PWD. Results: There was no difference between the two groups in terms of baseline demographic characteristics. Maximum P wave duration was higher in MS patients than controls (126 ± 6 vs. 122 ± 5 ms, p = 0.004). Minimum P wave duration was found to be similar in MS patients and healthy controls (72 ± 8 vs. 75 ± 8 ms, p = 0.2). Mean PWD value of MS patients was also found to be higher than those of controls (53 ± 10 vs. 47 ± 10 ms, p = 0.01). Conclusion: P wave duration and PWD was found to be statistically different in patients with MS and control subjects.