The Importance of Thiopurine S-Methyltransferase Gene Analysis before Azathioprine Therapy
Clinical Neuropharmacology, cilt.43, sa.4, ss.112-113, 2020 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 43 Sayı: 4
- Basım Tarihi: 2020
- Doi Numarası: 10.1097/wnf.0000000000000397
- Dergi Adı: Clinical Neuropharmacology
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, BIOSIS, EMBASE, MEDLINE, MLA - Modern Language Association Database, Psycinfo
- Sayfa Sayıları: ss.112-113
- Anahtar Kelimeler: neuromyelitis optica, azathioprine, pancytopenia
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Neuromyelitis optica is an inflammatory central nervous system syndrome associated with serum aquaporin-4 IgG antibody. Optic nerve and spinal cord involvement is typical. We report a 9-year-old girl with a diagnosis of neuromyelitis optica, who developed azathioprine-induced pancytopenia that was subsequently found to be caused by thiopurine-methyltransferase mutation.