A case with Henoch-Schonlein purpura concomitant with MTHFR C677T polymorphism MTHFR C677T poli̇morfi̇zmi̇ ve Henoch Schonlei̇n purpurasi
SENDROM, cilt.21, sa.4, ss.54-58, 2009 (Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 21 Sayı: 4
- Basım Tarihi: 2009
- Dergi Adı: SENDROM
- Derginin Tarandığı İndeksler: Scopus
- Sayfa Sayıları: ss.54-58
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Henoch-Schönlein purpura (HSP) is a leukocytoclastic vasculitic disease affecting mainly skin and many organs, like gastrointestinal system, joints, kidneys. A genetic tendency to hypercoagulability state and a predisposition to formation of thrombosis have been studied recently in several trials in HSP and other vasculitic syndromes. A case of HSP carrying MTHFR C677T polymorphism has been presented in this article, to pull attention to the impact of genetically acquired prothrombotic risk factors on clinical outcome and importance of steroid therapy has been discussed.