Congenital cardiac malformations in neonates with apparently isolated gastrointestinal malformations
Pediatrics International, cilt.51, sa.2, ss.260-262, 2009 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 51 Sayı: 2
- Basım Tarihi: 2009
- Doi Numarası: 10.1111/j.1442-200x.2008.02711.x
- Dergi Adı: Pediatrics International
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.260-262
- Anahtar Kelimeler: apparently isolated defect, congenital cardiac malformation, malformation of the gastrointestinal tract, neonate, non-syndromic
- Sağlık Bilimleri Üniversitesi Adresli: Hayır
Özet
Background The association of congenital cardiac malformations (CCM) with malformations of the gastrointestinal tract/abdominal wall is known. Nevertheless, the data presently available are derived from patient populations that include some special conditions known to be associated with a high rate of CCM. The aim of the present study was therefore to determine the incidence of cardiac malformations among neonates with apparently isolated malformations of the gastrointestinal tract/abdominal wall. Methods A total of 201 neonates with apparently isolated gastrointestinal malformations were screened on echocardiography. Result Thirty-six (17.9%) of the neonates were diagnosed as having a CCM. When the four most frequent gastrointestinal malformations were evaluated, a CCM was diagnosed in 11/69 (15.9%) with anal atresia, in 9/38 (23.7%) with tracheoesophageal fistula/esophageal atresia, in 2/25 (8%) with diaphragmatic hernia and in 5/17 (29.4%) with intestinal atresia. In 11 of 36 patients (30.6%) with CCM, the cardiac problems were hemodynamically significant, requiring anti-congestive and/or surgical treatment. Conclusion A significant number of neonates with apparently isolated gastrointestinal malformations had CCM. Because almost all patients with malformations of the gastrointestinal tract/abdominal wall require early surgical intervention, they should be evaluated on echocardiography to investigate CCM at the earliest opportunity. © 2008 Japan Pediatric Society.