Successful treatment of severe menorrhagia at menarche with recombinant factor VIIa in an adolescent girl with type III von Willebrand's disease
Blood Coagulation and Fibrinolysis, cilt.29, sa.5, ss.469-471, 2018 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 29 Sayı: 5
- Basım Tarihi: 2018
- Doi Numarası: 10.1097/mbc.0000000000000739
- Dergi Adı: Blood Coagulation and Fibrinolysis
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.469-471
- Anahtar Kelimeler: menorrhagia, recombinant factor VIIa, von Willebrand's disease
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Type III von Willebrand's disease (vWD) is an inherited bleeding disorder, which is frequently associated with menorrhagia in women. Treatment options include antifibrinolytics, desmopressin, von Willebrand factor/factor VIII concentrates and in intractable bleeding circumstances recombinant factor VIIa (rFVIIa). We present an adolescent case with type III vWD who had a menorrhagia at menarche that was refractory to the standard treatment and ultimately was treated with rFVIIa successfully.