The effect of house dust mite sensitization on skin dermis thickness in children with allergic respiratory diseases
Postepy Dermatologii i Alergologii, cilt.42, sa.1, ss.105-109, 2025 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 42 Sayı: 1
- Basım Tarihi: 2025
- Doi Numarası: 10.5114/ada.2025.147855
- Dergi Adı: Postepy Dermatologii i Alergologii
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE
- Sayfa Sayıları: ss.105-109
- Anahtar Kelimeler: house dust mite sensitization, skin barrier, skin thickness, children, allergy
- Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Introduction: An impaired skin barrier has been reported in allergic diseases. Aim: In this study, we aimed to evaluate dermis thickness in children with house dust allergy without skin symptoms. Material and methods: This cross-sectional study included children aged 4–18 years with asthma and/or allergic rhinitis. Participants were divided into three groups: healthy controls (n = 50), patients sensitized to house dust mites (n = 60), and patients with negative house dust mite tests (n = 48). The thickness of the dermis layers of the skin was measured at the cubital fossa using an ultrasound. Results: The median age and gender distribution were similar across the house dust mite-positive and -negative groups and the healthy control group. There was no significant difference between the groups in terms of dermis thickness (p = 0.053). Absolute eosinophils and eosinophil percentage were significantly negatively correlated with dermis (p < 0.05). There was no significant correlation between total IgE, house dust mite specific IgE and skin test values and skin thickness (p > 0.05). Conclusions: The findings of this study highlight the impact of house dust mite sensitization on skin thickness, offering potential contributions to the management and treatment strategies of allergic diseases.