Analysis of geographical variations in the epidemiology and management of non-valvular atrial fibrillation: Results from the RAMSES registry

Doğan, Volkan; Başaran, Özcan; Biteker, Murat; Karadeniz, Fatma; Hamidi, Mehmet; GÜRSOY, Mustafa; Öztürk, Müjgan; Aksan, Gökhan; Seyis, Sabri; BALLI, Mehmet; Alıcı, Mehmet; BOZYEL, Serdar; KIRMA, Cevat; Kalkan, Sedat; Tekkesin, Ahmet; Tekkesin, Ahmet; Cakıllı, Yasin; Cakıllı, Yasin; Turkkan, Ceyhan; Turkkan, Ceyhan; Demir, Vahit; Demir, Vahit; Calık, Feyza; Karaca, Oğuz; Helvacı, Fusun; Ayturk, Mehmet; Akay, Kadriye; Canga, Yiğit; Celebi, Savaş; ALTUNTAŞ, EMİNE; Guneş, Hacı; Bezgin, Tahir; Aksakal, Aytekin; Caka, Beytullah; ÇOLAK, AYŞE; Kaplan, Ozgur; Tatlısu, Adem; Gozubuyuk, Gokhan; DEMİRELLİ, Selami; Kaya, Adnan; Rencuzoğulları, İbrahim; Bayram, Zubeyde; Şimşek, Zeki; Civan, Murat; Batgharel, Ulaankhu; Ata, Ali; Gol, Gokhan; Mert, Gurbet; MERT, KADİR; Değirmencioğlu, Aleks; Candan, Ozkan; ÖZCAN ÇELEBİ, Özlem; DOĞAN, Cem; Yavuz, Fethi; Ulucan, Şeref; Arısoy, Arif; Şahin, Bingul; Ermiş, Emrah; Gokaslan, Serkan; Pektaş, İdris; Tanındı, Aslı; Tekin, Kamuran; Sancar, Kadriye; Altun, İbrahim; Cekic, Edip; Başaran, Nesrin

doi:10.14744/anatoljcardiol.2017.7709

Analysis of geographical variations in the epidemiology and management of non-valvular atrial fibrillation: Results from the RAMSES registry

Doğan V., Başaran Ö., Biteker M., Karadeniz F. Ö., Hamidi M., GÜRSOY M. O., ...Daha Fazla

Anatolian Journal of Cardiology, cilt.18, sa.4, ss.273-280, 2017 (SCI-Expanded, Scopus, TRDizin)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 18 Sayı: 4
Basım Tarihi: 2017
Doi Numarası: 10.14744/anatoljcardiol.2017.7709
Dergi Adı: Anatolian Journal of Cardiology
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
Sayfa Sayıları: ss.273-280
Anahtar Kelimeler: epidemiology, chronic disease, anticoagulant therapy
Sağlık Bilimleri Üniversitesi Adresli: Evet

Özet

Objective: This study aimed to determine the differences in terms of demographic characteristics and preferred stroke prevention strategies for patients with non-valvular atrial fibrillation living in seven geographical regions of Turkey. Methods: In total, 6273 patients were enrolled to this prospective, observational RAMSES study. The patients were divided into seven groups based on the geographical region of residence. Results: In terms of the geographical distribution of the overall Turkish population, the highest number of patients were enrolled from Marmara (1677, 26.7%). All demographic characteristics were significantly different among regions. Preferred oral anticoagulants (OACs) also differed between geographical regions; non-vitamin K OACs were preceded by warfarin in East Anatolia, Aegean, Southeast Anatolia, and Black Sea. Nearly one-third of the patients (28%) did not receive any OAC therapy. However, the number of patients not receiving any OAC therapy was higher in Southeast Anatolia (51.1%) and East Anatolia (46.8%) compared with other geographical regions of Turkey. Inappropriate use of OACs was also more common in East and Southeast Anatolia. Conclusion: This study was the first to show that the demographic differences among the geographical regions may result in different preferences of stroke prevention strategies in Turkey. OACs are still under- or inappropriately utilized, particularly in the eastern provinces of Turkey.