Success rate of outpatient weight management in obese patients with obstructive sleep apnea
Acta Medica Mediterranea, cilt.32, sa.5, ss.1705-1712, 2016 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 32 Sayı: 5
- Basım Tarihi: 2016
- Doi Numarası: 10.19193/0393-6384_2016_5_153
- Dergi Adı: Acta Medica Mediterranea
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.1705-1712
- Anahtar Kelimeler: Diet, Exercise, Obesity, Obstructive sleep apnea, Weight loss
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Introduction: Obesity is a modifiable risk factor for obstructive sleep apnea (OSA). The purpose of this study was to examine the success rate and the effects of an outpatient weight loss program on obese OSA patients. Materials and methods: This prospective study included 34 apneic obese patients (body mass index 33.7 ± 5.8 kg/m2, age 47.1 ± 8.7 years). Intervention program consisted of 12-week program of moderate intensity exercise (40-60% of HRR) and individualized diet. A weight loss of ≥ 3% from baseline was considered as "clinically significant weight loss" according with the guidelines of American College of Sports Medicine (ACSM). Polysomnographic, anthropometric and metabolic measurements were taken before and after the significant weight loss. Data were analyzed using the Chi square test, Wilcoxon signed ranks test and Mann Whitney U test. Results: Clinically significant weight loss was achieved by 18 patients (53%), and 16 patients (47%) were unsuccessful. It was significant that mild / moderate OSA patients were mostly successful (68%), while the majority of severe patients (75%) were unsuccessful (P = 0.016). There were significant improvements in anthropometric, metabolic and sleep parameters (apnea-hypopnea index, O2 desaturation index, Epworth sleepiness score) of successful patients after 12 weeks program. Conclusion: Outpatient weight loss programs are more convenient for patients with mild / moderate OSA. However, obese patients with severe OSA have more barriers to perform exercise. Inpatient weight loss program seems like a better option for obtaining effective weight loss in severe apneic patients.