A Comparison of 18F-FDG PET/CT and 68Ga-PSMA PET/CT in Detecting Osteonecrosis of the Jaw in a Patient With Prostate Cancer
Clinical Nuclear Medicine, cilt.49, sa.2, 2024 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 49 Sayı: 2
- Basım Tarihi: 2024
- Doi Numarası: 10.1097/rlu.0000000000004970
- Dergi Adı: Clinical Nuclear Medicine
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Anahtar Kelimeler: osteonecrosis, jaw, zoledronic acid, Ga-68-PSMA, F-18-FDG, PET/CT
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Medication-related osteonecrosis of the jaw (ONJ) is rare adverse effect of zoledronic acid. We present ONJ detected in a 65-year-old man with prostate cancer who underwent 18F-FDG PET/CT for metabolic characterization and to exclude a second primary malignancy of the liver lesion observed in 68Ga-PSMA PET/CT. ONJ has high metabolic activity on 18F-FDG PET/CT and no PSMA receptor activation on the 68Ga-PSMA PET/CT. In this case, we wanted to underline the importance of 18F-FDG PET/CT imaging of medication-related ONJ in patients receiving zoledronic acid therapy and to emphasize that rapid and appropriate treatment can be provided.