Cancer in autoimmune diseases
Autoimmunity and Cancer, NOVA Publications , ss.127-145, 2022
- Yayın Türü: Kitapta Bölüm / Araştırma Kitabı
- Basım Tarihi: 2022
- Yayınevi: NOVA Publications
- Sayfa Sayıları: ss.127-145
- Anahtar Kelimeler: Autoimmune diseases, Cancer, Inflammation
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
The unregulated inflammatory process leads to the development of two devastating conditions, cancer and autoimmune diseases. Cancer arises as a result of uncontrolled growth due to many mutations and changes in the metabolic balance of the tumor cell and its surroundings. Autoimmune diseases are chronic inflammatory disorders characterized by immune-mediated self-tissue destruction due to loss of self-tolerance. Although the exact mechanism is not yet clearly understood, it is known that autoimmune diseases are associated with a high risk of malignancy. Similar inflammatory conditions are involved in the development of cancer and autoimmune diseases. In this article, it is aimed to discuss the relationship between the most common autoimmune diseases and malignancies and to mention the increasing types of cancer associated with autoimmunity.