Activity of Neutrophil NADPH Oxidase in Iron-Deficient Anemia
Biological Trace Element Research, cilt.96, sa.1-3, ss.109-115, 2003 (Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 96 Sayı: 1-3
- Basım Tarihi: 2003
- Doi Numarası: 10.1385/bter:96:1-3:109
- Dergi Adı: Biological Trace Element Research
- Derginin Tarandığı İndeksler: Scopus
- Sayfa Sayıları: ss.109-115
- Anahtar Kelimeler: iron-deficiency anemia, iron supplementation, neutrophil function, NADPH oxidase
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
This study was designed to measure the effects of iron supplementation on respiratory burst in iron-deficient anemia. The performance of neutrophils was evaluated by measuring the activity of NADPH oxidase in 18 patients with iron-deficient anemia before and after body iron stores are saturated. The activity of NADPH oxidase was significantly lower in pretreatment patients relative to controls (p<0.05). The activity increased after iron supplementation to levels that had no significant differences relative to controls.