Value of diffusion-weighted MRI in the differentiation of benign and malign breast lesions
Wiener Klinische Wochenschrift, cilt.123, sa.21-22, ss.655-661, 2011 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 123 Sayı: 21-22
- Basım Tarihi: 2011
- Doi Numarası: 10.1007/s00508-011-0053-5
- Dergi Adı: Wiener Klinische Wochenschrift
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.655-661
- Anahtar Kelimeler: Breast cancer, breast mass, magnetic resonance imaging, diffusion-weighted imaging, apparent diffusion coefficient
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Introduction: Our purpose was to determine whether diffusion-weighted MR imaging (DWI) could be used in differentiation of benign and malign breast lesions. Materials and Methods: 41 women patients were included in the study. 45 lesions were diagnosed by biopsy; 25 (55.5%) of these lesions were malignant and 20 (44.5%) were benign. The apparent diffusion coefficient (ADC) values of these lesions were prospectively compared with their histopathological results. Results: Differentiation of the malignant and benign masses revealed that the threshold value of the ADC was 1.0 × 10- 3 mm 2/s, its sensitivity was demonstrated as 95%, specificity as 100%, positive predictive as 100%, negative predictive as 94% and accuracy rate as 97%. Conclusions: DWI improves diagnostic accuracy of the conventional breast MRI. ADC measurements may be useful for differentiation of the malign and benign masses. © Springer-Verlag 2011.