Role of impression cytology method in the assessment of follow up and severity of symptoms for allergic rhinitis Allerji̇k ri̇ni̇tte taki̇p ve semptom şi̇ddeti̇ni̇n deǧerlendi̇ri̇lmesi̇nde i̇mpresyon si̇toloji̇si̇ metodu
Nobel Medicus, cilt.7, sa.3, ss.18-21, 2011 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 7 Sayı: 3
- Basım Tarihi: 2011
- Dergi Adı: Nobel Medicus
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.18-21
- Anahtar Kelimeler: Allergic rhinitis, Cytology, Diagnosis, Impression cytology
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Objective: Impression cytology (IC) is an easily repeated technique for investigating several pathologies of conjunctiva and nasal mucosa. We aimed to find an easy reliable and objective method to evaluate severity of symptoms in allergic rhinitis. For this purpose we investigated usefulness of impression cytology as an diagnostic and follow up tool in patients with allergic rhinitis. Material and Method: Thirty patients with allergic rhinitis were evaluated with both impression cytology and nasal biopsy. After medication, impression cytology and excisional biopsies were repeated, and results were compared. Results:: A correlation was observed between biopsy and impression cytology slides before (r=0.72, p=0.000) and after medication (r=0.66, p=0.000). Following the therapy, biopsy scores (z=-4.11, p=0.000) and impression cytology scores (z=-3.50, p=0.0005) were significantly lower than to the earlier scores of the same patients. But no correlation was observed between the severity of pre and post-treatment symptoms and IC and nasal biopsy scores (p>0.05). Conclusion: The results of this study is compatible with the allergic rhinitis and it's Impact on Asthma (ARIA) documentation on clinical evaluation of the severity of allergic rhinitis (AR) symptoms. However, in cases where optional nasal biopsy is considered, it shows that IC can be used reliably. Impression cytology is a quick, simple, painless, and noninvasive technique. It can be preferred to biopsy.