Association between Systemic Immune-Inflammation Index (SII) and secondary haemorrhage risk after tonsillectomy


GÜMÜŞSOY M., Yagız Agayarov Ö., ÇUKUROVA İ.

Journal of Laryngology and Otology, cilt.139, sa.10, ss.971-975, 2025 (SCI-Expanded, Scopus)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 139 Sayı: 10
  • Basım Tarihi: 2025
  • Doi Numarası: 10.1017/s0022215125102879
  • Dergi Adı: Journal of Laryngology and Otology
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, BIOSIS, CINAHL, EMBASE, MLA - Modern Language Association Database
  • Sayfa Sayıları: ss.971-975
  • Anahtar Kelimeler: lymphocyte, neutrophil, platelet, post-operative haemorrhage, tonsillectomy
  • Sağlık Bilimleri Üniversitesi Adresli: Evet

Özet

Objectives This study evaluates the relationship between Systemic Immune-Inflammation Index and secondary tonsillar haemorrhage after tonsillectomy. Methods Sixty pediatric patients with secondary haemorrhage and 60 without bleeding were grouped for comparative analysis. Laboratory parameters and Systemic Immune-Inflammation Index values were collected preoperatively, on the bleeding day and on the control day, then compared. Results Secondary haemorrhage occurred in 60 patients (3.11 per cent), with a mean age of 8.85 ± 3.07 years. Bleeding occurred at 8.63 ± 2.32 days post-operatively (range: 72 hours–21 days). Tonsillectomy day: Neutrophil count and Systemic Immune-Inflammation Index were significantly higher in the haemorrhage group (p < 0.001). Haemorrhage vs. tonsillectomy day (haemorrhage group): Platelet, neutrophil and Systemic Immune-Inflammation Index increased, while lymphocytes decreased (p < 0.001). Haemorrhage vs. control day: Neutrophil count and Systemic Immune-Inflammation Index remained significantly higher (p < 0.001). Conclusion Systemic Immune-Inflammation Index, a novel inflammatory marker, may help predict post-tonsillectomy haemorrhage risk.