Heterotopic bone formation in two cases of colon carcinoma


ALPER M., AKYÜREK N., Patiroǧlu T., Yüksel O., Belenli O.

Scandinavian Journal of Gastroenterology, cilt.35, sa.5, ss.556-558, 2000 (SCI-Expanded, Scopus)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 35 Sayı: 5
  • Basım Tarihi: 2000
  • Doi Numarası: 10.1080/003655200750023859
  • Dergi Adı: Scandinavian Journal of Gastroenterology
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.556-558
  • Anahtar Kelimeler: Colon, Mucinous adenocarcinoma, Osseous metaplasia, Radiotherapy, Signet- ring-cell carcinoma
  • Sağlık Bilimleri Üniversitesi Adresli: Hayır

Özet

Heterotopic bone formation is rare in the gastrointestinal tract. We here present the clinical and pathologic details of a 56-year-old male patient with mucinous adenocarcinoma of the colon and a 70-year-old male patient with colon metastasis previously operated on for signet-ring-cell carcinoma of the stomach who was treated with radiotherapy postoperatively. Both of them showed diffuse bone metaplasia. Heterotopic bone formation is usually present with mucin-producing benign or malignant tumors. The pathogenesis of osseous metaplasia is not well known; however, it is speculated that the extravasation of mucin may have a stimulatory role.