Progresses on Polymer Nanocomposites: Drug Delivery Systems and Sensitive Detections
Handbook of Polymer and eramic Nanotechnology: Volume 1,2, Springer International Publishing Ag, ss.381-401, 2021
- Yayın Türü: Kitapta Bölüm / Araştırma Kitabı
- Basım Tarihi: 2021
- Doi Numarası: 10.1007/978-3-030-40513-7_18
- Yayınevi: Springer International Publishing Ag
- Sayfa Sayıları: ss.381-401
- Anahtar Kelimeler: Drug analysis, Drug delivery, Polymer nanocomposites
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Polymers are vital material class in academic and commercial terms. Polymers can be obtained in many different morphologies depending on the synthesis methods. In advanced nanotechnology, the importance of monomers capable of reacting with many functional groups is significant. In recent years, efforts to combine nanomaterials with polymers have increased. In general, carbon nanotubes, graphene, and fullerenes have received increased interest due to nanocarbon materials containing quantum dots, unique structural properties, and exceptional physicochemical properties. Polymeric composite nano fibers with superior electrical conductivity, high porosity and unique matte structure have demonstrated numerous advantages and promising features in tissue engineering and sensor design. Composites obtained by combining two or more materials having different physicochemical properties can be separated into polymeric, ceramic, and metallic materials depending on the structure of the matrix phase. Among these composites, polymer types are commonly used in a wide variety of technical applications because polymers as matrix phase provide advantages over other materials such as workability, allowing the composites to be converted into intricate, lightweight components. Composite materials, due to their superior properties and versatility, have shown an increasing interest for various applications in environmental improvement. In recent years a strong emphasis has been placed on the development of polymeric nanocomposites where at least one of the dimensions of the filler material has nanometer order. In general, the unique combination of properties of nanomaterials, such as the size, mechanical properties, and low concentrations required to affect the change in a polymer matrix, has attracted much interest in the field of nanocomposites when combined with the advanced characterization and simulation techniques currently available. The extraordinary versatility of the nanocomposites allows them to be used as drug delivery systems. But these systems must be noncorrosive, nontoxic, and easy to remove if necessary for biomedical applications. Thus, a polymer nanocomposite must meet certain design and functional criteria, including biocompatibility, biodegradability, mechanical properties, and, in some cases, aesthetic demands. In this chapter, we provide an overview of the use of polymer-based composites in drug analysis and highlight the properties of polymer nanocomposites as drug delivery systems. The structure of the polymer nanocomposites was also identified.