Prognostic value of 18F-FDG PET/CT for identifying high- and low-risk endometrial cancer patients
Ginekologia Polska, cilt.87, sa.7, ss.493-497, 2016 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 87 Sayı: 7
- Basım Tarihi: 2016
- Doi Numarası: 10.5603/gp.2016.0032
- Dergi Adı: Ginekologia Polska
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.493-497
- Anahtar Kelimeler: PET/CT, endometrial cancer, prognosis, SUVmax
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Objectives: To assess the usefulness of adding PET/CT as a preoperative test for determining the extent of endometrial cancer and discriminating low- and high-risk patients to identify candidates for surgical staging. Material and methods: We retrospectively reviewed 86 patients with pathologically proven endometrial cancer who had undergone preoperative 18F-FDG PET/CT. The prognostic relationships between PET/CT parameters and pathology reports were assessed. Results: The SUVmax was significantly higher in patients with FIGO stage IB or higher compared with those with stage IA; for stage III-IV compared with stage I-II; and for patients with lymph node metastasis compared with those without lymph node metastasis. Using 6.70 as a cut-off for SUVmax, low-risk patients can be identified with a sensitivity of 92.9%. Conclusions: PET/CT imaging can be used not only for determining malignancy and lymph node involvement but also for determining candidates for surgical staging with high sensitivity.