Anaphylactic shock due to hepatitis B immunoglobulin in a newborn
Journal of Maternal-Fetal and Neonatal Medicine, cilt.23, sa.10, ss.1257-1259, 2010 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 23 Sayı: 10
- Basım Tarihi: 2010
- Doi Numarası: 10.3109/14767051003653260
- Dergi Adı: Journal of Maternal-Fetal and Neonatal Medicine
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.1257-1259
- Anahtar Kelimeler: Hepatitis B immunoglobulin, anaphylaxis, newborn, adverse effect
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Hepatitis B immunoglobulin (HBIG) is administered for the passive immunisation of all infants born to HBsAg-positive mothers within 12h of birth. Adverse effects of HBIG are very rare. In this study, we report a newborn (a female, 33 weeks' gestation and 2030g birth weight) developing anaphylaxis after HBIG administration. The mother was a Hepatitis B virus (HBV) carrier. Hypotension and erythematous rash developed 7min after HBIG administration. Reporting the first anaphylaxis case in newborns due to HBIG in literature, we suggest the condition be taken into account, and requisite precautions should be taken against this probable complication in the newborn. © 2010 Informa UK, Ltd.