Evaluation of mediastinal lymphadenopathy from long-term radiological findings in covid-19 Evaluación de la linfadenopatía mediastínica a partir de hallazgos radiológicos a largo plazo en COVID-19
Cirugia y Cirujanos, cilt.93, sa.6, ss.636-643, 2025 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 93 Sayı: 6
- Basım Tarihi: 2025
- Doi Numarası: 10.24875/ciru.25000018
- Dergi Adı: Cirugia y Cirujanos
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, Directory of Open Access Journals
- Sayfa Sayıları: ss.636-643
- Anahtar Kelimeler: Mediastinal lymphadenopathy, SUVmax. Surgical indication, Positron emission tomography, Post-COVID-19
- Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Objective: Mediastinal lymphadenopathy (MLAP) has been reported in post-COVID-19 patients. In this study, the relationship between post-COVID-19 infection and MLAP was investigated in patients who had been diagnosed with MLAP and decided to undergo surgery. Methods: The study included the records of 140 patients who had been diagnosed with MLAP and were decided for surgical treatment. Demographic findings, reverse transcription-polymerase chain reaction (PCR) test results, chest X-ray, thorax computed tomography (CT) findings, positron emission tomography (PET)-CT findings, and histopathological results were recorded. Results: SUVmaxvalue above 2.5 was 15 times more common in patients with positive PCR test results than in patients with negative results. Abnormal chest X-ray results were associated with a 9.3-fold increase in the number of patients, and the number of patients with abnormal pathology results was 33.9 times higher than those with normal results. Conclusions: Post-COVID-19 and MLAP (SUVmax3-5) were shown to be associated independently of age, gender, comorbidities, and disease outcomes. MLAP lesions in patients with COVID-19 demonstrated SUVmaxvalues that were 10-fold higher compared to patients without COVID-19. Determining reliable SUVmaxvalues in patients with severe COVID-19 may help guide clinical decisions, tailor therapeutic approaches, and avoid unnecessary surgical indications.