Synthesis of some 2-[(benzazole-2-yl)thioacetylamino]thiazole derivatives and their antimicrobial activity and toxicity
European Journal of Medicinal Chemistry, cilt.39, sa.3, ss.267-272, 2004 (Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 39 Sayı: 3
- Basım Tarihi: 2004
- Doi Numarası: 10.1016/j.ejmech.2003.11.001
- Dergi Adı: European Journal of Medicinal Chemistry
- Derginin Tarandığı İndeksler: Scopus
- Sayfa Sayıları: ss.267-272
- Anahtar Kelimeler: thiazole, benzothiazole, benzimidazole, benzoxazole, antimicrobial activity
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Some 2-[(benzazole-2-yl)thioacetylamino]thiazole derivatives (III) were synthesized by reacting 4-methyl-2-(chloroacetylamino)thiazole derivatives (I) with benzazol-2-thiole (II) in acetone in the presence of K2CO 3. The chemical structures of the compounds were elucidated by 1H NMR and FAB+-MS spectral data. The prepared compounds were tested for antimicrobial activity and toxicity. © 2003 Elsevier SAS. All rights reserved.