Live birth rates of low prognosis patients according to POSEIDON criteria; A retrospective cohort study


Seven B., Gulerman C., ÖZGÜ ERDİNÇ A. S., Yilmaz N., Engin-Ustun Y.

Journal of Gynecology Obstetrics and Human Reproduction, cilt.49, sa.7, 2020 (SCI-Expanded, Scopus)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 49 Sayı: 7
  • Basım Tarihi: 2020
  • Doi Numarası: 10.1016/j.jogoh.2020.101817
  • Dergi Adı: Journal of Gynecology Obstetrics and Human Reproduction
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, PASCAL
  • Anahtar Kelimeler: Poor ovarian response, POSEIDON, Live birth rate, Infertility
  • Sağlık Bilimleri Üniversitesi Adresli: Evet

Özet

Objective: The aim of the study was to compare the outcome of assisted reproductive treatment fresh cycles, in patients with low prognosis which were stratified according to the POSEIDON (Patient-Oriented Strategies Encompassing IndividualizeD Oocyte Number) criteria. Materials and methods: This retrospective cohort study including all fresh assisted reproductive treatment cycles age < 44 years, between January and December 2017 was carried out from patient records of Zekai Tahir Burak Women Health Care Education and Research Hospital IVF Clinic. A total of 525 IVF cycles were analyzed and 276 patients fulfilling the POSEIDON criteria for poor ovarian response (POR) were included in the study. Results: Implantation rate, clinical pregnancy rate, and early miscarriage rate were similar in four POSEIDON groups. Live birth rate (LBR) is statistically higher in unexpected POR groups and also significantly higher in POSEIDON group 3 when compared with POSEIDON group 4. Conclusion: LBRs are not homogenous in low prognosis patients fulfilling POSEIDON criteria and it seems unexpected POR groups have the most favorable pregnancy outcomes. In unexpected POR groups, age was not a determinant factor in IVF success but in the expected group, age is the most powerful determinant factor.