Corneal perforation due to chronic graft-versus-host disease after allogenic bone marrow transplantation Allojenik kemik iliǧi transplantasyonu sonrasi kronik graft-versus-host hastaliǧina baǧli korneal perforasyon
Gulhane Medical Journal, cilt.48, sa.3, ss.166-168, 2006 (Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 48 Sayı: 3
- Basım Tarihi: 2006
- Dergi Adı: Gulhane Medical Journal
- Derginin Tarandığı İndeksler: Scopus, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.166-168
- Anahtar Kelimeler: Allogenic stem cell transplantation, Corneal perforation, Graft-versus-host disease, Hyperbaric oxygen therapy
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Dry eye associated with chronic graft-versus-host disease is the most frequently observed complication after allogenic bone marrow transplantation. The other important ocular complications are recurrent corneal epithelial defects, corneal ulcer and corneal melting. A 25-year-old female patient admitted with the complaints of stinging and burning sensation in her both eyes. The patient had allogenic bone marrow transplantation with the diagnosis of chronic myelocytic leukemia two years ago. Examination of the patient revealed punctate epithelial keratopathy, dry eye and posterior subcapsular cataract in her both eyes. We determined common skin dryness, dermatitis and Cushingoid face in her examination. In this article a case of dry eye and corneal perforation developing due to chronic graft-versus-host disease after allogenic bone marrow transplantation is presented, and combination treatment of tacrolimus, steroid and hyperbaric oxygen therapy performed after primary surgery is discussed. © Gülhane Askeri Tip Akademisi 2006.