An investigation of thyroid and parathormone hormones and related biochemical factors in individuals with and without symptoms indicative of temporomandibular disorder admitted to the internal medicine department


Özkan S., Taş S., Kumbasar S., Gümüş M., Kaynak B. A.

Cranio - Journal of Craniomandibular and Sleep Practice, cilt.43, sa.6, ss.1032-1042, 2025 (SCI-Expanded, Scopus)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 43 Sayı: 6
  • Basım Tarihi: 2025
  • Doi Numarası: 10.1080/08869634.2025.2499300
  • Dergi Adı: Cranio - Journal of Craniomandibular and Sleep Practice
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, BIOSIS, CINAHL, MEDLINE
  • Sayfa Sayıları: ss.1032-1042
  • Anahtar Kelimeler: Temporomandibular disorders, thyroid hormones, parathormone, minerals, vitamins
  • Sağlık Bilimleri Üniversitesi Adresli: Evet

Özet

Objective: To investigate the effect of parathormone and thyroid hormones, along with their associated biochemical factors in individuals with and without symptoms indicative of temporomandibular disorder (TMDs) admitted to the internal medicine department. Methods: The study involved 416 participants with symptoms indicative of TMDs and 415 controls. Serum concentrations of anti-thyroid peroxidase antibody (Anti-TPO Ab), free triiodothyronine, free thyroxine, thyroid-stimulating hormone, parathyroid hormone, calcium, sodium, potassium, magnesium, phosphorus, vitamin D, vitamin B12, folate, creatine kinase, haemoglobin, ferritin, C-reactive protein and sedimentation rate were analysed. Results: The serum level of anti-TPO Ab was found to be elevated in participants with symptoms indicative of TMDs in comparison to controls (p <.001). However, no significant differences were observed in the other parameters assessed between the two groups (p >.05). Conclusion: Serum concentrations of parathormone and thyroid hormones associated biochemical factors are not affected in participants with symptoms indicative of TMDs except Anti-TPO Ab.